Hard to imagine a world without The Oprah Winfrey Show on weekday afternoons.

But that's exactly what the world's going to be like after Sept. 9, 2011, which will mark the end of Winfrey's 25th season as host of her eponymous daytime talk show—and her last show altogether.

We can just hear the Rolodexes twirling as the folks at Harpo Productions start lining up celebrities to tape "goodbye, Oprah" messages.

"Yes, it's true that she will be ending her show in September 2011," a rep for Harpo tells E! News. "She will be speaking about it on tomorrow's live show."

Where will the big shots share, cry and couch-jump now? How will mere mortals get free cars?!